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New York Giants Indianapolis Colts Betting Pick

March 17th, 2026
 

In their last action, Indianapolis was a 34-24 loser on the road against the Texans. They failed to cover the 1.5-point spread as favorites, while the combined score (58) was profitable news for OVER bettors.

New York Giants Indianapolis Colts Betting Pick

This should be a close game between the two Manning brothers and I look for it to be a high scoring battle.  The game will come down to the Colts D, if they can hold their own Payton will have no time throwing the ball in a victory covering the 4.5 spread.  With that said the Colts have a major part of the defence missing if Bob Sanders doesn’t play.   My Bet is still on the Colts to cover, I think their defence with or without Bob will have huge motivation to step their game up.

The New York Giants and the Indianapolis Colts will both be gunning for a victory on Sunday when they meet at Lucas Oil Stadium.

Oddsmakers currently have the Colts listed as 4½-point favorites versus the Giants, while the game’s total is sitting at 48½.

Last time out for New York, they were a 31-18 winner as they battled the Panthers at home. The Giants covered in the match as a 5.5-point favorite, while 49 combined points moved the game OVER for totals bettors.

SMART CHART
NYG TEAM IND
31.0 PTS FOR 24.0
18.0 PTS AGNST 34.0
13.0 DIFF. -10.0
258.0 PASS YDS 419.0
118.0 RUSH YDS 44.0
148.0 PASS D 98.0
89.0 RUSH D 257.0
-1.0 TO DIFF 0.0
BETTING TRENDS


NEW YORK Giants
NY Giants are 4-8 SU in their last 12 games
NY Giants are 3-9 ATS in their last 12 games
The total has gone OVER in 5 of the NY Giants last 5 games
NY Giants are 1-4 SU in their last 5 games on the road
NY Giants are 18-7 SU in their last 25 games on the road
NY Giants are 1-4 ATS in their last 5 games on the road
The total has gone OVER in 4 of the NY Giants last 5 games on the road
INDIANAPOLIS Colts
Indianapolis is 2-4 ATS in its last 6 games
The total has gone OVER in 6 of Indianapolis’s last 8 games
Indianapolis is 2-4 SU in its last 6 games
Indianapolis is 16-4 SU in its last 20 games
Indianapolis is 15-2 SU in its last 17 games at home

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