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Giants Bills Betting Pick

March 16th, 2026
 

New York Giants Buffalo Bills Betting Pick

 

Giants Bills Betting Odds

The Point spread for this game is set at 3 points in favor of the home team New York giants. The total combined score for this match is set at 50 points.  Find out what our expert's betting pick is below.

I have found the best point spread for betting on the Bills +3 (-110) from bodog 
The best point spread for betting on the Giants -2.5 (-105) is at betonline

 

Giants Bills Betting Pick

 

I wrote last week that the Bills were due for a letdown against the Eagles, and I feel like they wanted to, because there is no way the Eagles should make that game close after Vick threw 4 picks. This is the week the Bills have a letdown. The Giants have been inconsistent this year, mirroring the play of their Quarterback.

The Giants offense has not played as well as expected this year, or at least as well as I had expected. The running game for the Giants has been horrid this year. I attribute that to having too much Ahmad Bradshaw and not enough of the Juggernaut Brandon Jacobs. Also the Giants are hurting a bit from letting Steve Smith (non babypuncher) go to the eagles. He was the perfect slot guy for Eli the way Welker is the perfect slot guy for Brady.

The Giants defense has been very mediocre this year. They've been killed by injuries so far this year. Nothing about this defense really suggests that they'll beat Buffalo, but ya know fuck it. They are at home at least so there's that. Osi Umenyiora is probable this week too so he could play and probably like rape the Bills left tackle into a Rick Ross seizure. How that would work I do not know.

And then there's the mothafuckin' Bills. God, before I had Sunday ticket the Bills ruined so many Sundays for me. I'd be all excited for like the game of the week and then because of my geographical position (In Canada) I got the Bills game shown on 3 different fucking channels. Simulcasting is the devil.

My Pick

Bottom Line: I don't feel too strongly on this game, but the Giants are at home and the Bills are due for heartbreak city before too long. I think the Giants take it behind a solid performance by Eli.

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